In Vitro Evaluation of Analgesic Activity of the Methanol Extract of Pileamicrophylla (L.) Liebm. in Swiss Albino Mice

Abstract

Due to the availability of the plant Pileamicrophylla (L.) Liemb in Bangladesh, the present study was aim to investigatein vitroanalgesic activity of the methanol extract of Pileamicrophylla (L.) Liebm. analgesic activity was conducted at the doses of 200 and 400 mg/kg body weight usingSwiss albino mice as animal model by two thermal (hot plate and tail immersion test) methods. Overall, the extract showed significant analgesic activity compared to standard drug (Diclofenac-Na, 5 mg/kg body weight). Thus, the obtained findings of this present work provide a rationale for the use of this plant for medicinal purposes and encourage us for further investigations to obtain more fruitful results.

Keywords: Pileamicrophylla, Urticaceae, analgesic activity, Swiss albino mice,

Diclofenac-Na

Cite this Article

Sadia Afreen Chowdhury. In Vitro Evaluation of Analgesic Activity of the Methanol Extract of Pileamicrophylla (L.) Liebm. in Swiss albino mice. Research & Reviews: Journal of Computational Biology. 2017; 6(3): 12–15p.