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Histopathological Findings of Endometrium and its clinico-pathological co-relation

Usha v Shinde, Ravi Ranjan Singh


Background: Endometrial diseases are ranked among the most common gynecological disorders that affect women globally. These diseases cut across all age groups and contribute significantly to increased morbidity and mortality. Aim: To establish a database with respect to histopathological patterns and frequencies of endometrial diseases in women of various age groups. Materials and Methods: This prospective study was conducted in a Tertiary care Hospital in Sangli (Maharashtra) for a period of Six months. Results: A total of 125 cases were analyzed. Patients' age ranged from 18 to 60 years. Out of these, 58/125 (46.4 percentage) cases were seen in reproductive and 59/125 (47.2 percentage) in perimenopausal age groups while 08/125(6.4 percentage) was encountered in postmenopausal age group. The most common clinico-radiological diagnosis was abnormal uterine bleeding (AUB) which was seen in 62/125 (49.6 percentage) of cases. Overall, proliferative phases endometrium was commonest histopathological finding seen in 75/125 (60 percentage) cases, followed by 18/125 (14.4 percentage) cases of disordered proliferative endometrium. Malignancy was seen in 2/125 (1.6 percentage) cases which were seen in postmenopausal age group and was diagnosed as Endometrioid endometrial carcinoma. Remaining nine cases were diagnosed as Simple endometrial hyperplasia 04/125 (3.2 percentage), Complex endometrial hyperplasia 03/125 (2.4 percentage), Endometrial polyp 02/125(1.6 percentage), Product of conception 05/125(4.0 percentage), Hydatidiform mole 1/125(0.8 percentage) and Atrophic endometrium in 02/125 (1.6 percentage) cases. One (0.8 percentage) case was reported as inadequate for opinion. Conclusion: Histopathological evaluation of endometrial samples is important for proper evaluation and management of patient.


Keywords: Endometrial biopsy and curettage, post menopausal bleeding, abnormal uterine bleeding, endometrial polyps, histopathology, Proliferative endometrium, Secretory endometrium

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Shinde UV, Singh RR. Histopathological Findings of Endometrium and its Clinicopathological Correlation. Research & Reviews: A Journal of Health Professions. 2017; 7(3): 33–38p.

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