Histopathological Findings of Endometrium and its clinico-pathological co-relation

Abstract

Background: Endometrial diseases are ranked among the most common gynecological disorders that affect women globally. These diseases cut across all age groups and contribute significantly to increased morbidity and mortality. Aim: To establish a database with respect to histopathological patterns and frequencies of endometrial diseases in women of various age groups. Materials and Methods: This prospective study was conducted in a Tertiary care Hospital in Sangli (Maharashtra) for a period of Six months. Results: A total of 125 cases were analyzed. Patients' age ranged from 18 to 60 years. Out of these, 58/125 (46.4 percentage) cases were seen in reproductive and 59/125 (47.2 percentage) in perimenopausal age groups while 08/125(6.4 percentage) was encountered in postmenopausal age group. The most common clinico-radiological diagnosis was abnormal uterine bleeding (AUB) which was seen in 62/125 (49.6 percentage) of cases. Overall, proliferative phases endometrium was commonest histopathological finding seen in 75/125 (60 percentage) cases, followed by 18/125 (14.4 percentage) cases of disordered proliferative endometrium. Malignancy was seen in 2/125 (1.6 percentage) cases which were seen in postmenopausal age group and was diagnosed as Endometrioid endometrial carcinoma. Remaining nine cases were diagnosed as Simple endometrial hyperplasia 04/125 (3.2 percentage), Complex endometrial hyperplasia 03/125 (2.4 percentage), Endometrial polyp 02/125(1.6 percentage), Product of conception 05/125(4.0 percentage), Hydatidiform mole 1/125(0.8 percentage) and Atrophic endometrium in 02/125 (1.6 percentage) cases. One (0.8 percentage) case was reported as inadequate for opinion. Conclusion: Histopathological evaluation of endometrial samples is important for proper evaluation and management of patient.

Keywords: Endometrial biopsy and curettage, post menopausal bleeding, abnormal uterine bleeding, endometrial polyps, histopathology, Proliferative endometrium, Secretory endometrium

Cite this Article

Shinde UV, Singh RR. Histopathological Findings of Endometrium and its Clinicopathological Correlation. Research & Reviews: A Journal of Health Professions. 2017; 7(3): 33–38p.