Effect of Cyclandelate on Sudden Hearing Loss: Study of Five Cases

Abstract

Sudden sensorineural hearing loss is one of the most perplexing and controversial, unsolved mystery. It is an idiopathic hearing loss of sensorineural origin, greater than 30 dB in three contiguous frequencies that occurs in less than three days. Cyclandelate is a peripheral vasodilator and improves blood flow. Pre- and post-treatment (4 weeks) audiological assessment was done. The standardized protocol was Tab. Cyclandelate, Methylcobalamine and Cetrizine. Pre-treatment pure-tone audiometry showed moderate loss in two ears, severe in one ear, and profound in two ears. Post-treatment pure-tone audiometry, hearing was normal in one ear, mild loss in three ears and moderate in one ear. The average hearing improvement of 70 dB was achieved. If Cyclandelate is given alone it is effective in 80% patients as compared to long list of treatment regime. It is cost effective and key to unsolved mystery.

Keywords: Sudden hearing loss, cyclandelate, peripheral vasodilator