Treatment of Generalized Eruptive Keratoakantoma Using Acitretin Dosage

Abstract

Keratoakantoma (KA) is a squamous neoplasia, variant of squamous cell skin cancer. In typical cases it is found to be solitary, filled with keratin, dome-shaped craterform papule with a diameter of 1–2 cm. KA regresses spontaneously within 3 months after the onset of the disease. Atypical KA persist, rarely regress spontaneously and can be giant, multinodular, centrifugum marginatum, subungual, as well as multiple, including Generalized Eruptive Keratoakantoma (GEKA). In the present study, out of the 256 patients diagnosed with KA, the GEKA was diagnosed only in two cases. In the first case, an 82-year-old patient, Acitretin was administered and a pronounced clinical effect was observed. Acitretin was prescribed in dose 25 mg once a day for 3 months. After 1 month the itching disappeared and after 3 months, there was a complete regress of the eruption.

Keywords: GEKA, Acitretin, Keratoakantoma

Cite this Article

Molochkov Anton Vladimirovich, Molochkova Yulia Vladimirovna, Medzhidova Surat Magomedovna. Treatment of Generalized Eruptive Keratoakantoma Using Acitretin Dosage. Research & Reviews: A Journal of Immunology. 2019; 9(1): 27–32p.