Study of Platelet Count in Dengue Fever, Function and Their Importance in Hemostasis

Abstract

Dengue infection is a major vector-borne disease. Compatible hematological discovery comprises of vasculopathy, thrombocytopenia, and coagulopathy. The study comprises of 60 patients and all the cases were studied in the Department of Pathology, Kachchhi laboratory, Amreli, Gujarat, India. In this study, out of 60 cases, there were 12 cases of IgG positive and 31 cases of IgM positive. In which seven males had IgG infection and 18 males had IgM infection while five female had IgG infection and 13 female had IgM infection. There were 12 cases of IgM negative and five cases of IgG negative. In which seven males had IgM negative and two males had IgG negative; and three female had IgG negative and five females had IgM negative. Among the total 60 patients, IgM & IgG positive patients were 25(58.13%) males and 18(41.86%) females. IgM & IgG antibodies negative patients were 52.94% males and eight (47.05%) females. Here total positive patients were 43(71.66%) and total negative patients were 17(28.33%). Dengue virus is the causative agent of a wide spectrum of clinical manifestations. The major pathophysiological changes in severe dengue include leakage of plasma and abnormal hemostasis. Vasculopathy, platelet abnormalities, and coagulopathy are responsible for abnormal hemostasis in dengue patients.

Keywords: Platelet, dengue, coagulation, DIC, fever

Cite this Article

Miral Patel, Ankita Bhatiya. Study of Platelet Count in Dengue Fever, Function and Their Importance in Hemostasis. Research & Reviews: A Journal of Immunology. 2019; 9(1): 1–3p.