Prevalence of Oral Candidiasis by Candida albicans in Patients with Type 2 Diabetes Mellitus Visiting Mahakali Zonal Hospital

Abstract

Patient with type 2 diabetes mellitus are at consistent risk of oral candidiasis, dental caries and dysfunction. Candiadisis is caused by different species such as Candida albicans, C. tropicalis, C. glabrata, C. dubliniensis. Nevertheless, C. albicans is the most frequent causative agent for candidiasis in human. Present work was undertaken to investigate Candida albicans infection among type 2 diabetic mellitus patients in Mahendranagar, Kanchanpur. Methods: A total of 103 oral samples were collected cross-sectionalfrom the patients at Mahakali zonal hospital from July 2015 to February 2016 and cultured in Potato Dextrose Agar to isolate the fungus. The fungus was characterized by colonial characteristics, gram staining and germ tube test. Results: Prevalence of C. albicans was found to be 70.8% among the patients of type 2 diabetic mellitus with 45 males and 28 females. The male patients are at high risk of infection, probably due to hard physical work as compared to female. Among the patients having high fasting blood glucose level 100-139 mg/dl were the most susceptible for infection. Similarly, C. albicans infection was highly prevalent among type 2 diabetes mellitus patients with high frequency among smoking and alcohol habits. Conclusion: Patients must play an important role in minimizing the yeast infection by regular checkup, dental care, and consultation better control of blood sugar and also to educate others about the common ailment that can adversely affect if not controlled earlier.

Keywords: Diabetes, Candida albicans, Fungus, Infection, zonal hospital.

Cite this Article
Laxman Bhatt, Tek Raj Awasthi, Lok Raj Bhatt. Prevalence of Oral Candidiasis by Candida albicans in Patients with Type 2 Diabetes Mellitus Visiting Mahakali Zonal Hospital. Research & Reviews: A Journal of Microbiology & Virology. 2020; 10(1): 1–9p.