Evaluation of Antibiofilm Potential of Alginate Encapsulated Selenium Nanoparticles

Abstract

Biofilm interfere in antibiotic therapy, undergo gene transformation to become highly virulent, develop quorum sensing and protect bacteria from host immunity. To combat these biofilms the encapsulation method of nanoparticles formation using PEG can be used as they are better alternative to chemical and physical methods. In the present study, the antibiofilm and antioxidant properties of the selenium nanoparticles produced by using probiotics have been evaluated. Transmission electron microscopy (TEM) images of the prepared selenium nanoparticles showed a uniform distribution and their spherical morphology. Due to the small size of the nanoparticles, these could be easily taken up by the bacterial and fungal biofilm leading to their disruption. Nanoparticles showed inhibition of biofilm in the evaluated microbes as evident by decrease in protein and carbohydrate content.

Keywords: selenium, nanoparticles, bacterial biofilms, antimicrobial activity

Cite this Article

Sharma A, Sharma S, Kaur R. Evaluation of antibiofilm potential of alginate encapsulated selenium nanoparticles. Research & Reviews: A Journal of Microbiology and Virology. 2018; 8(2): 16–21p.