Ganglioneuroma of Lip: A Rare Benign Tumor

Abstract

Ganglioneuroma is a rare benign tumor arising from neural crest sympathogonia, which are completely undifferentiated cells of the sympathetic nervous system. However, ganglioneuromas themselves are fully differentiated neuronal tumors that do not contain immature elements. Ganglioneuroma most frequently occurs in the abdomen, however these tumors can grow at anywhere sympathetic nervous tissue is found. It occurs in patients between 10 and 30 years of age. It is exceedingly uncommon in the skin. Here, we present a case of ganglioneuroma of lower lip in a 30 year old female who was presented with painless progressive swelling of lower lip with negative history of trauma. Excision biopsy was done under local anesthesia and tissue specimen was sent for histopathology examination in 10% formalin solution. Microscopic picture was consistent with ganglioneuroma of lower lip. Surgical resection of tumor is the primary mode of treatment.

Keywords: Ganglioneuroma, neural Crestsympathogonia

Cite this Article

 Garima Tonk, Rajni Joshee, Kishore Khatri et al. Ganglioneuroma of Lip: A Rare Benign Tumor. Research & Reviews: Journal of Oncology and Hematology. 2017; 6(3): 1–4p.