Histopathological Effects of Silver Nanoparticles on Gills and Liver of Freshwater Fingerlings Catla catla (Ham.)

Abstract

Fish is the best biomarker to identify the adverse effect on surroundings. Here, the fingerlings of major carp (Catla catla) were used as a model in the present work to investigate the toxicity caused by silver nanoparticles (AgNPs). The fish exposed to different concentrations of 10 μg/L and 30 μg/L AgNPs for 15 days were sampled at days 5, 10 and 15 for histology. This exposure caused organ injuries, and the kind of pathologies observed include aneurisms, necrosis in the secondary lamellae of the gills, clumping in cartilaginous core, congestion of secondary lamellae, and lifted up interlamellar epithelium. Liver histology exhibits various abnormalities including, congestion of hepatocytes, pyknotic cells, severe hemorrhage and cellular clumping in central lobular vein, parenchymal vacuolization, focal necrosis and dilation of sinusoid.

Keywords: AgNPs, Catla catla, liver, gill, histopathology

Cite this Article

A. Patel, U. Dani, A. Bahadur. Histopathological Effects of Silver Nanoparticles on Gills and Liver of Freshwater Fingerlings Catla catla (Ham.). Research and Reviews: Journal of Toxicology. 2016; 6(1): 18–27p.