A Comprehensive Review on Therapeutic Utilities and Purificatory Procedures of Strychnos nux-vomicaLinn. (Kupeelu) as Described in Indian Systems of Medicine

Swarnendu Mitra, Rabinarayan Acharya

Abstract


Strychnosnux-vomica Linn. (Loganiaceae), known as Kupeelu in Ayurveda, has been commonly employed in Ayurvedic pharmacopoeia since long. It is a deciduous tree widely distributed in India and found throughout topical India and additionally in Sri Lanka, Thailand, Cambodia and Vietnam. In this review, an endeavour has been made to explore the therapeutic utilities of Strychnosnuxvomica and to put emphasis on especially different methods of purificatoryproceduresas mentioned in Ayurveda. It is observed that seeds of Strychnosnux-vomica are used as an ingredient of compound formulations of Ayurvedic system of medicine indicated for nervous debility, paralysis and weakness of limbs, sexual weakness, dyspepsia, dysentery and chronic rheumatism. Additionally, it is employed in the treatment of anemia, asthma, bronchitis, colic, intermittent fever, hysteria, etc., in a specific therapeutic dose. In higher doses, it produces tetanic convulsions ultimately resulting in death. Kupeelu has been described as a toxic plant in Ayurveda and certain purificatoryprocedures (Shodhana) of the seeds are considered mandatory before its administration.


Keywords


Kupeelu, nuxvomica, strychnine, tetanic convulsions,Shodhana.

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References


Sharma SN, Shastri KN. Rasa Tarangini,11th edn. New Delhi. MotilalBanarasidas Publication. 2000. 163– 164p.

Anonymous. The Ayurvedic Formulary Of India. 1st edition. New Delhi. Govt. of India. 1978. 172p.

Anonymous, Database of Indian Medicinal Plants. New Delhi. Documentation and Publication Division CCRAS. 2005. 5. 139p.

SabnisMukund. Chemistry & Pharmacology of Ayurvedic Medicinal Plants. 1st edn. Varanasi. ChaukhambaAmarabharatiPrakas han. 2006. 455–456p.

Chunekar K.C. BhavaprakashNighantu. Varanasi. ChoukhambaBharati Academy. Reprint 2002. 568p

Evans C Williams. Pharmacognosy. 16th edn. Elsevier Limited. 2009. 399p.

Sharma R.K, Das Bhagwan. CharakaSamhita, Text with English translation & critical exposition based on CakrapaniDutta’s Ayurveda Dipika. Varanasi. Chowkhamba Sanskrit Series Office. Reprint 2008. 1. 24p.

Shastri JLN. DravyagunaVijnana. 1st edn. Varanasi. ChoukhambaOrientalia. 2009. 1. 320p.

Sudarshan S.R. EncyclopaediaOf Indian Medicine. 1st edn. Bangalore. Popular Prakashan. 2005. 155p.

Sharma P.V. DravyagunaVijnana. Varanasi. ChoukhambaBharati Academy. Reprint 2003. 2. 84p.

ChatterjeeAsima, PakrashiSatyesh Chandra. The Treatise On Indian Medicinal Plants. New Delhi. Publications & Information Directorate. 4.84–85p.

Dastur J.F. Useful Plants of India & Pakistan. Bombay. D.B Taraporevala Sons & Co. Private Ltd. 1985. 149p.

SanayalDevaprasad, GhoseRasbehari. Vegetable Drugs Of India. Calcutta. The Medical Publishers. 1934. 528p.

Kirtikar KR, Basu BD. Indian Medicinal Plants. 2nd edn. Dehra Dun. Bishen Singh Mahendra Pal Singh. 2003. 3. 1646p.

Anonymous. The Wealth of India. New Delhi. National Institute of Science Communication, Council of Scientific & Industrial Research. 1998. 10. 62p.

PandeyGyanendra. Anti-Aging Herbal Drugs of India. 1st edn. Delhi. Sri Satguru Publication. 2002. 248p.

Dutta UC. MateriaMedica Of Hindus. 3rd edn. Varanasi. Krishnadas Academy. 1980. 2. 200p.

BhattaKrishnaram, Bhatta R Kaladhara (Ed.). Siddhabhesajamanimala. 3rd edn. Varanasi.ChowkhambaKrishnadas Academy. 2003. 167p.

Ibidem (ref.14). 195p.

Ibidem (ref.14). 199p.

ShastriAmbikadatta. BhaisajyaRatnavali. 19th edn. Varanasi. ChaukhambaPrakashan. 2008. 341p.

Krishna Sri Gopal, PrakashSatyartha (commentator). RasendraSarSangraha. 1st edn. Varanasi. Krishnadas Academy. 1994. 533–534p.

Ibidem (ref.17). 1185p.

Ibidem (ref.17). 366p.

Ibidem (ref.17). 367p.

Ibidem (ref.17). 585p.

Ibidem (ref.17). 603p.

Ibidem (ref.17). 874p.

Ibidem (ref.1). 684-685p.

Ibidem (ref.1). 686-687p.

Ibidem (ref.1). 227-229p.

Anonymous. Said Hakim Mohammed (Ed.). Hamdard Pharmacopoeia of Eastern Medicine. 2nd ed. Delhi. Sri Satguru Publication. 1997. 101p.

Ibidem (ref.28). 148p.

Ibidem (ref.28). 259p.

http://www.answers.com/library/Alternave Medicine Encyclopedia-cid-56400 cited on 2011 June 18.

Ibidem (ref.2). 459p.

Qeensland Government, Department of Primary Industries and Fisheries. Dog Aware Fact [cited 2011 June 10]. http://www.dpi.qld.gov.au/documents/Bi osecurity_EnvironmentalPests/IPA-Wild- Dog-Fact-Sheet-Strychnine.pdf

AcharyaJadavjiTrikamji. Siddhayog Samgraha. 13th edn. Allahabad. Shree BaidyanathAyurvedBhavan Ltd. 2008. 163p.

Sharma S.N., Shastri K.N. Rasa Tarangini. MotilalBanarasidas Publication. 176–177p.

Ibidem (ref.1). 174–175p.

Parikh Gopinath. BanousadhiRatnakar. 2nd edn. Vijaygara. SudhanidhiKaryalaya. 2006. 2. 371p.

Ibidem (ref.1). 172–173p.

TrivediKrishnaprasad. DhanwantariBanausadhiVisesanka. Vijaygara. DhanwantariKaryalaya. 1963. 2. 270p.

Anonymous. A. Hafiz Haji Musa Bhadkodravi (Sa.)(Ed.). Adu, AnjirnaGuno-Vishesatao. Gujarat. Haji Md. Rafiq Musa Patel Publication. 20– 21p.

Mitra S., Shukla V.J., Acharya R.N. Effect of purificatory measures through cow’s urine and milk on Strychnine and Brucine content of Kupeelu (Strychnosnux-vomicalinn.) seeds.Afr J Tradit Complement Altern Med, 2012, 9(1):105-111p.

Mitra S., Shukla V.J. &Acharya R.N.Effect of Shodhana(processing) on Kupeelu (Strychnosnuxvomica Linn.) with special reference to strychnine and brucine content.AYU, 2011, 32(3), 110-115p.

Mitra S., Shukla V.J., Acharya R.N. Role of Castor oil in Processing (Shodhana) of Kupeelu(Strychnosnuxvomica Linn.) Seeds: An Approach of Traditional Ayurveda. IJAM, 2011,2 (2), 62-71p.

Nadkarni.K.M. Indian MateriaMedica. 3rd edn. Bombay. Popular Prakashan Pvt. Ltd. 1976. 1. 1175p.


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