Oral Manifestation of Crohn's Disease: A Case Report and literature review Oral Manifestation of Crohn's Disease: A Case Report and literature review
DOI:
https://doi.org/10.37591/rrjod.v12i1.2455Keywords:
Crohn’s diseases, corticosteroids, oral manifestations, differential diagnosis, investigationsAbstract
Crohn’s disease is a chronic granulomatous inflammatory disorder that can affect any part of the gastrointestinal tract from the mouth to the anus with the most common localization being the ileocecal region. This is a case of 17 years old young Sudanese boy presented to Khartoum Teaching Dental Hospital complaining of a swelling on the left side of his face And on the lower lip.Histopathological result show non-caseating giant cell granulomas. Treatment was initiated by systemic corticosteroid that resulted in complete resolution of the Swelling after 2weeks.the patient on regular follow-up.
References
Fei Zhou, Zhengjin Liu, et al. A case report of atypical chron’s disease diagnosed by endoscopic ultrasonography. Int J Clin Exp Med. 2016; 9(10): 20362–20366.
Tomasz Machand Katarzyna Szczeklik. Crohn’s Disease and Its Oral Manifestations. J Gastroenterol Hepatol Endosc. 2017; 2(2): 1012.
Safar B, Sands D. Perianal Crohn's Disease. Clin Colon Rectal Surg. 2007; 20(4): 282–93.
Muhvić-Urek M, Tomac-Stojmenović M, Mijandrušić-Sinčić B. Oral pathology in inflammatory bowel disease. World J Gastroenterol. 2016; 22(25): 5655–67.
Asquith P, Thompson RA, Cooke WT. Oral manifestations of Crohn's disease. Gut. 1975; 16(4): 249–54.
Michailidou E, Arvanitidou S, Lombardi, et al. Oral lesions leading to the diagnosis of Crohn disease: report on 5 patients. Quintessence Int. 2009; 40(7): 581–88. 7. Marc Fakhoury, Rebecca Negrulj, et al. Inflammatory bowel disease: clinical aspects and treatments. J Inflamm Res. Jun 2014; 7: 113–120.
Ogura Y, Bonen DK, Inohara N, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn’s disease. Nature. 2001; 411(6837): 603–606.
Ponder A, Long DM. A clinical review of recent findings in the epidemiology of inflammatory bowel disease. Clin Epidemiol. 2013; 5: 237–247.
Weinstock JV, Summers R, Elliott DE. Helminths and harmony. Gut. 2004; 53(1): 7–9.
Shoda R, Matsueda K, Yamato S, Umeda N. Epidemiologic analysis of Crohn disease in Japan: increased dietary intake of n-6 polyunsaturated fatty acids and animal protein relates to the increased incidence of Crohn disease in Japan. Am J Clin Nutr. 1996; 63(5): 741–745.
Hovde O, Moum B. Epidemiology and clinical course of Crohn’s disease: results from observational studies. World J Gastroenterol. 2012; 18(15): 1723–1731.
Roxanne Bavarian, Ahmed S. Sultan, Alessandro Villa. A persistent swelling of the lower lip. J Am Dent Assoc. 2018; 150(5): 378–382.
Irving PM, Gearry RB, et al. Review article: appropriate use of corticosteroids in Crohn’s disease. Journal compilation. 2007; 26(3): 313–329.
Sandborn WJ, Feagan BG, Lichtenstein GR. Medical management of mild to moderate Crohn’s disease: evidence-based treatment algorithms for induction and maintenance of remission. Aliment Pharmacol Ther. 2007; 26(7): 987–1003.
Fakhoury M, Coussa-Charley M, et al. Use of artificial cell microcapsule containing thalidomide for treating TNBS-induced Crohn’s disease in mice. Curr Drug Deliv. 2014; 11(1): 146–153.
Ljung T, Karlén P, Schmidt D, et al. Infliximab in inflammatory bowel disease: clinical outcome in a population based cohort from Stockholm County. Gut. 2004; 53(6): 849–853.
Bauditz J, Wedel S, Lochs H. Thalidomide reduces tumour necrosis factor alpha and interleukin 12 production in patients with chronic active Crohn’s disease. Gut. 2002; 50(2): 196–200.
Canavan C, Abrams KR, Mayberry J. Meta-analysis: colorectal and small bowel cancer risk in patients with Crohn’s disease. Aliment Pharmacol Ther. 2006; 23(8): 1097–1104.
Jess T, Gamborg M, Matzen P, et al. Increased risk of intestinal cancer in Crohn’s disease: a meta-analysis of population-based cohort studies. Am J Gastroenterol. 2005; 100(12): 2724–2729.
Downloads
Published
Issue
Section
License
Declaration and Copyright Transfer Form
(to be completed by authors)
I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.
- I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.
- I/We Author(s ) have niether given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).
- I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.
- I/We also agree to the authorship of the article in the following order:
Author’s name
1. ________________
2. ________________
3. ________________
4. ________________
| We Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal. |