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Effect of Sodium Fluoride and Cellulose Gum Toothpaste over Regular SLA Toothpaste in Reducing Xerostomia-A Retrospective Cohort Study
Abstract
Our aim is to study the effect of mildly flavoured sodium fluoride 0.2% and cellulose gum on patient suffering from chronic xerostomia in comparison to effect of general sodium Laurel sulphate containing toothpaste on same condition patient. A controlled study population was used for the investigation. The baseline for this study is to estimate the risk of developing xerostomia or worsening of the condition in patient already suffering from xerostomia due to cancer therapy or hypo ptyalism or hyposalivation. Sodium Laurel sulphate also called sodium alkylethersulphate, is an anionic detergent or surfactant used in products like personal care or for industrial uses. It is inexpensive and is generally used in toothpaste as a foaming agent. SLS must come into touch with the skin for an excessively lengthy period of time before it is deemed a concern. Generally it is used as a foaming agent in toothpaste , facewash etc. Generally its side effect is observed only when it is brought in direct contact with the skin. However the side effects take a long-time to be observed since it is contact duration with the area is for a very short duration of time. However it is enough to make micro chronic changes over a duration of times. Recent advance in the field of natural polymers used to maintain or restore oral health has given rise to use of cellulose gum usage on toothpastes. When selecting ingredients, one should consider it's safety for all oral tissues gums, mucosa, pulp and bone and also eliminating risk of diffusion of such harmful component. This could lead to adverse chronic effect if taken every day systemically.
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References
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DOI: https://doi.org/10.37591/rrjod.v13i2.2960
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