Anti-Tumour and Anti-Bacterial Activity of Some Ethno-Medicinal Plants

Abstract

Background: Every year, millions of people are diagnosed with cancer, leading to death in a majority of the cases. Because of the high death rate associated with cancer and serious side effects of chemotherapy and radiation therapy, many cancer patients seek alternative methods of treatment. Regarding the safety and effectiveness of natural therapies, the researchers are more interested in the use of natural medicine. In the present investigation, the anti-tumour and anti-bacterial effects of five different plant extracts at different concentrations have been evaluated.
Results: The result of the present study show that all the tested fractions inhibited tumor formation in the potato disc assay. Annona squamosa was the most efficient in inhibiting up to 75% at concentration of 1 mg/ml and 50% at concentration of 0.1 mg/ml; Boerhavia diffusa with an inhibition of 60% and 32% at concentrations of 1 mg/ml and 0.1 mg/ml, respectively. Centella asiatica has inhibition of 18% at concentration 0.1 mg/ml.
Conclusions: The anti-tumor potential demonstrated by the extracts respective plant species in the present study is in line with the traditional uses. These plants could be used as a source of potent anti-tumor agents for anti-tumor drug development.

Keywords: Medicinal plants, cancer, anti-tumour potato disc assay, Agrobacterium tumefaciens, Anti-bacterial

Cite this Article
Patnaik Amit, Sharma Hanuman Prasad, Kumari Priyank et al. Anti-Tumour and Anti-Bacterial Activity of Some Ethno-Medicinal Plants. Research & Reviews: A Journal of Immunology. 2017; 7(3): 16–22p.