Tuberculosis Treatment Outcomes among TB Patients at FenoteSelam District Hospital, West Gojjam Zone, Amhara, Northwest Ethiopia

Abstract

Introduction: Tuberculosis is a major public health problem throughout the world. One third of the world’s population is estimated to be infected with bacilli and hence at risk of developing active disease. It is the second leading cause of death from an infectious disease worldwide after HIV, which caused an estimated 1.8 million deaths. The main reason for this is the high rate of death as an unsuccessful outcome. Incomplete treatment carries a risk of development of resistance and increased disease transmission.

Objective: The main aim of this study was to assess tuberculosis treatment outcomes among TB patients at FenoteSelam district hospital West Gojjam, Amhara, Northwest Ethiopia.

Methods: Institutional based retrospective cohort study was conducted from May 2014 to June 2014. About 651 records were included in to the cohort. Data were collected from medical records and patients’ chart using standard checklist. The data were entered into Epidata version3.1and then it was exported to SPSS version 20.0 software. Logistic regression analysis model was fitted to assess possible associations and the strength of association was measured using odds ratio with 95% CI.

Result: From the total participants, 433 (66.5%) of TB diseased patients had successfully treatment outcome. Two hundred eighteen (33.5%) patients had unsuccessful treatment outcome. About 369 (56.7%) of participants were male and 282 (43.3%) were female. Age of participants was associated with TB treatment outcome. Those variables had p value ≤ 0.2 were considered for multiple logistic regression analysis.

Conclusion: Treatment outcomes of DOTS program among TB patients at FenoteSelam district hospital showed that almost all patients were taken their TB treatment by direct observation of the health care providers. Those patients belong to age group 25–34 and ≥55 years had high prevalence of defaulted treatment outcome as compare to the age groups of 0–14 years. Patients who had smeared negative pulmonary tuberculosis had relatively high rate of default and death.

Keywords: Tuberculosis, anti TB drug, treatment default, treatment failure, cures

Cite this Article

Desalegne Amare. Tuberculosis Treatment Outcomes among TB patients at FenoteSelam District Hospital, West Gojjam Zone, Amhara, Northwest Ethiopia. Research and Reviews: Journal of Medicine. 2016; 6(3): 1–8p.