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Efficacy of Apium graveolens (Bekh Karafs) in Hyperuricemia: A Randomized Single Blind Standard Control Study

M. A. Siddiqui, Nasimul H., Arshid Iqbal Wani


Hyperuricemia may induce certain complications like gouty arthritis, nephrolithiasis and uric
acid nephropathy. Owing to its dreadful complications, the researchers of different system of
medicine are concentrating themselves for the development of new drugs, which can lower
uric acid level in blood. The main aim of the study was to assess the efficacy of Apium
graveolens in lowering the serum uric acid level in blood. The present study was a single
blind, randomized standard control study carried out at the department of Medicine
(Moalajat) in National Institute of Unani Medicine Bengaluru. A total of 40 patients of
hyperuricemia of either gender, above 20 years and below 70 years of age were selected and
randomly assigned to control and test group; comprising 20 patients in each group. Test
group was treated with Apium graveolens 10 gm once a day in the form of decoction, whereas
control group was given Allopurinol, 1 tablet each 100 mg three times a day for 45 days. All
the patients were assessed on subjective and objective parameters. The result was analyzed
statistically using Wilcoxan signed rank test and Chi square test, RM ANOVA, and Student t
test. At the end of the study, significant reductions in joint pain and serum uric acid levels
were observed in test as well as in control group when compared to baseline. However, no
statistically significant differences were observed between test and control groups. The overall
effect of the Apium graveolens was found quite encouraging in the treatment of
Keywords: Hyperuricemia, Apium graveolens, Bekh karafs, gout

Cite this Article
M.A Siddiqui, Nasimul H., Arshid Iqbal
Wani. Efficacy of Apium graveolens
(Bekh Karafs) in Hyperuricemia: A
Randomized Single Blind Standard
Control Study. Research & Reviews:
Journal of Medicine. 2017; 7(2): 7–12p.

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