Assessment of Thyroid Disorders in Pre-Diabetic Patients of South Gujarat Region

Abstract

Background: Coexistence of both thyroid disorders and pre-diabetic condition can make control of blood sugar more difficult and converting pre-diabetics into diabetic patients. Aim of the study is to assess the T3, T4 and TSH level and thyroid disorders including hypothyroidism, subclinical hypothyroidism and subclinical hyperthyroidism in pre-diabetic patients in south Gujarat region. Material and Method: The study carried out at biochemistry department SMIMER medical college using 20–60 years of total 200 numbers of population which includes 100 normal individual (group-1) sand 100 pre-diabetic patients(group-2) as per WHO criteria. Serum T3, T4, TSH level estimation by immunoassay method and blood glucose level by glucose oxidase peroxidase method was done. Results: 17% subjects were having thyroid dysfunction amongst pre-diabetes. Serum T3 and T4 were higher in control groups in compare to case and TSH is higher in case compare to control subjects but statistically these values are not significant. The distribution of different condition like hypothyroidism, subclinical hyperthyroidism and subclinical hypothyroidism within case group and control group subjects were compared. In our study, significant difference for TSH has been found between pre-diabetics and control and more percentage of thyroid disorder are reported in pre-diabetic than control group. It is crucial to apply screening test to find out thyroid disorder amongst pre-diabetics and to manage it effectively, so it can reduce the prevalence of diabetes mellitus.

Keywords: Pre-diabetic, hypothyroid, hyperthyroid

Cite this Article

Sheetal Patel, Nisha Parmar, Kalpesh Nakrani et al. Assessment of Thyroid Disorders in Pre-Diabetic Patients of South Gujarat Region. Research & Reviews: Journal of Medical Science and Technology. 2018; 7(1): 13–20p.