Screening of Mean Platelet Volume as a Prognostic Marker in Patients with Type 2 Diabetes Mellitus

Abstract

In this study platelets volume and its important role as a diagnostic marker was estimated in the prevalence of type 2 diabetes mellitus (T2DM) which are associated with mean platelet volume (MPV). The aim of the study was to investigate if platelets were activated in diabetes and its associated vascular complications by measuring the MPV in the diabetics compared to the non-diabetics, and to determine the correlation of MPV with fasting serum glucose (FSG), HbA1c and duration of diabetes in the diabetic patients, respectively. Aim: High throughput screening of mean platelet volume as a prognostic marker in patients with type 2 diabetes mellitus in studied population. Materials and Methods: The study was performed in 250 patients of T2DM (cases) and 250 non-diabetic controls. T2DM patients were separated into two groups based on their HbA1c levels; group A consisted of patients with HbA1c levels ≤7% and group B belonged of patients with HbA1c levels >7%. Results: In this dissertation we have found MPV value significantly higher in group B over the both non-diabetics along with group A. MPV has recorded a strong positive correlation with HbA1c in the diabetes record. It is also very clearly recorded in this study that MPV was found increased in T2DM cases. Conclusions: This study was mainly focused on the association between MPV and HbA1c in the T2DM patients. The results obtained by this study have stated that MPV can be a beneficial prognostic marker of cardio-vascular complication in the patients with T2DM disease.

Keywords: Fasting serum glucose (FSG), HbA1c, MPV (mean platelet volume), thromboembolism, marker, type 2 diabetes mellitus

Cite this Article

Nosad Husen, Mamta Padhy. Screening of Mean Platelet Volume as a Prognostic Marker in Patients with Type 2 Diabetes Mellitus. Research & Reviews: Journal of Medical Science and Technology. 2020; 9(1): 47–52p.