Antibacterial Potentiality of SourSop Leaf and Fruit Extract: A Review
Keywords:
Annona muricata, antibacterial activity, extraction, SourSop, bio-active compounds, Gram- negative bacteria, and Garm-positive bacteriaAbstract
SourSop is scientifically known as Annona muricata Linnaeus, which is a highly potent plant with a wide range of activities especially against cancer. The plant has many health benefits and all its parts have been utilized for treating various diseases. It is also used popularly to make various food items like ice creams and beverages. Lately, it has been explored for its antibacterial and anticancer properties by researchers worldwide. The phytochemicals present in the plant have equipped the plant with various activities like: antioxidant, anti-bacterial, anti-cancer, and so forth. The present review focuses on summarizing various pharmacological studies conducted to extract bioactive compounds from the plant using different extraction methods. The bioactive compounds present demonstrate the ability to combat bacterial strains belonging to both Gram-negative and Gram-positive categories. The review provides a comprehensive overview of the diverse pharmacological investigations conducted, shedding light on the extraction methods employed to harness the bioactive properties of the plant for potential therapeutic applications.References
Mat Daud NNNN, Ya’akob H, Mohamad Rosdi MN. Acetogenins of Annona muricata leaves: characterization and potential anticancer study. Integr Cancer Sci Ther. 2016; 3 (4): 543–551.
Mathew J, George R, Theruvil R, Padavil TC, Tomy L, Kurian A. Antibacterial activity of leaf extract of Annona muricata & Simarouba glauca on Enterococcus faecalis. J Contemp Dent Pract. 2016; 17 (8): 650–653. doi: 10.5005/jp-journals-10024-1906, PMID 27659082.
Padma P, Pramod NP, Thyagarajan SP, Khosa RL. Effects of the extract of Annona muricata and Petunia nyctaginiflora on herpes simplex virus. J Ethnopharmacol. 1998; 61 (1): 81–83. doi: 10.1016/s0378-8741(98)00013-0, PMID 9687085.
Adewole SO, Caxton-Martins EA. Morphological changes and hypoglycaemic effects of Annona muricata Linn. Annonaceae; 2006. leaf aqueous extract on pancreatic B-cells of Streptozotocin- treated diabetic rats.
Vijayameena C, Subhashini G, Loganayagi M, Ramesh B. Phytochemical screening and assessment of antibacterial activity for the bioactive compounds in Annona muricata. Int J Curr Microbiol Appl Sci. 2013; 2 (1): 1–8.
Oliveira AP, Sá I, Pereira DM, Gonçalves RF, Andrade PB, Valentão P. Exploratory studies on the in vitro anti-inflammatory potential of two herbal teas (Annona muricata L. & Jasminum grandiflorum L.) and relation with their phenolic composition. Chem Biodivers. 2017; 14 (6). doi: 10.1002/cbdv.201700002, PMID 28256049.
Gowsalya P, Sathya T. In-vitro Antioxidant, antibacterial and anticancer properties of leaf extract Annona muricata. Int J Adv Sci Eng. 2021; 8: 12119–12126.
Lim TK. Edible medicinal and non-medicinal plants. 2012; 1: 190–200. doi: 10.1007/978-90-481- 8661-7.
Lombor TT, Olaitan IN, Ede RA. Proximate composition, antinutrient content and functional properties of SourSop flour as Influenced by oven and freeze drying methods. Curr Res Nutr Food Sci. 2014; 2 (2).
Ssenyange CW, Namulindwa A, Oyik B, Ssebuliba J. Plants used to manage Type II diabetes mellitus in selected districts of central Uganda. Afr Health Sci. 2015; 15 (2): 496–502. doi: 10.4314/ahs.v15i2.24, PMID 26124796.
Gavamukulya Y, Wamunyokoli F, El-Shemy HA. Annona muricata: is the natural therapy to the most disease condition including cancer growing in our backyard? A systematic review of its research history and further prospects. Asian Pac J Trop Med. 2017; 10 (9): 835–848. doi: 10.1016/j.apjtm.2017.08.009, PMID 29080611.
Mutakin M, Fauziati R, Fadhilah FN, Zuhrotun A, Amalia R, Hadisaputri YE. Pharmacological activities of SourSop (Annona muricata Lin.). Molecules. 2022; 27 (4). doi: 10.3390/molecules27041201, PMID 35208993.
de Sousa OV, Vieira GD, de Jesus R G de Pinho J, Yamamoto CH, Alves MS. Antinociceptive & anti-inflammatory Activities of the ethanol extract of Annona muricata L. Leaves in Animal models. Int J Mol Sci. 2010; 11 (5): 2067–2078. doi: 10.3390/ijms11052067, PMID 20559502.
Adewole SO, Ojewole JA. Protective effects of Annona muricata Linn. (Annonaceae) leaf aqueous extract on serum lipid profiles and oxidative stress in hepatocytes of streptozotocin-treated diabetic rats. Afr J Tradit Complement Altern Med. 2008; 6 (1): 30–41. doi: 10.4314/ajtcam.v6i1.57071, PMID 20162039.
Shaw D, Graeme L. Pharmacovigilance of herbal medicine. J Enthopharmacology. 2012; 140 (3): 513–518.
Moghadamtousi SZ, Fadaeinasab M, Nikzad S, Mohan G, Ali HM, Kadir HA. Annona muricata: a review of its traditional uses; isolated acetogenins and biological activities. Int J Mol Sci. 2015; 16 (7): 15625–15658.
Hasmila I, Natsir H, Soekamto NH. Phytochemical analysis and antioxidant activity of soursop leaf extract (Annona muricata Linn.). J Phys Conf S. 2019; 1341 (3): 032027. doi: 10.1088/1742- 6596/1341/3/032027.
Rupprecht JK, Hui YH, McLaughlin JL. Annonaceous acetogenins: a review. J Nat Prod. 1990; 53 (2): 237–278. doi: 10.1021/np50068a001, PMID 2199608.
Tambun R, Alexander V, Ginting Y. Performance comparison of maceration method, soxhletation method, and microwave-assisted extraction in extracting active compounds from soursop leaves (Annona muricata): a review, Conference Series. Mater Sci Eng. 2021; 1122: 012095.
Agu KC, Okolie PN. Proximate composition, phytochemical analysis, and in vitro antioxidant potentials of extracts of Annona muricata (Soursop). Food Sci Nutr. 2017; 5 (5): 1029–1036. doi: 10.1002/fsn3.498, PMID 28948021.
Gajalakshmi S, Vijayalakshmi S, Devi Rajeswari V. Phytochemical and pharmacological properties of Annona muricata: a review. Int J Pharm Pharm Sci. 2012; 4 (2): 3–6.
Rodriguez-Perez JL, Millones-Gomez PA. Antibacterial effect of Annona muricata L. leaves on Streptococcus mutans ATCC25175 strains. J Clin Diagn Res. 2019; 13 (10): zc13–zc16.
Uchegbu RI, Akalazu J, Ukpai K, Iwu I. Antimicrobial Assessment of Annona muricata fruits and its chemical composition. Asian J Med Health. 2017; 3 (1): 1–7. doi: 10.9734/AJMAH/2017/31927.
Primasari A, Nasution M, Hidayati Arbi N, Sari DP, Basyuni M. The effectiveness of SourSop leaf extract against growth of aggregatibacter actinomycetemcomitans ATCC6514 in vitro. Asian J Pharm Clin Res. 2018; 11 (12). doi: 10.22159/ajpcr.2018.v11i12.28435.
de CC Pinto N, Campos LM, Evangelista ACS, Lemos ASO, Silva TP, Melo RCN et al. Antimicrobial Annona muricata L. extract targets the cell membrane of Gram-positive and Gram- negative bacteria. Ind Crops Prod. 2017; 107: 332–340.
Downloads
Published
Issue
Section
License
Declaration and Copyright Transfer Form
(to be completed by authors)
I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.
- I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.
- I/We Author(s ) have niether given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).
- I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.
- I/We also agree to the authorship of the article in the following order:
Author’s name
1. ________________
2. ________________
3. ________________
4. ________________
| We Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal. |