Study of Leucocyte Count, Serum Bilirubin and C-Reactive Protein Values in Preoperative Diagnosis of Acute Appendicitis
DOI:
https://doi.org/10.37591/rrjos.v4i1.1426Abstract
Acute appendicitis is one of the most common surgical emergencies all over the world. In appendicular perforation, morbidity and mortality increases significantly. A prompt diagnosis and early surgery can only be done if clinical findings are supported by laboratory tests. To estimate preoperative serum leukocyte count, total bilirubin and C-reactive protein levels in patients with clinical diagnosis of acute appendicitis and compare them with histopathological diagnosis postoperatively. Cross sectional study was conducted in Department of general surgery, NIMS medical college, Jaipur, during the period of September 2013 to August 2014. Patients were admitted with clinical diagnosis of acute appendicitis. Total 100 patients with clinical diagnosis of acute appendicitis were studied. Acute appendicitis was more in 2nd and 3rd decade of life with male to female ratio 3:2. TLC was increased more than 10000 in 73% patients, bilirubin was more than one in 82% patients and c- reactive protein was positive in 82% patients. Appendix was acutely inflamed in 76% patients on sonography and 76% on histopathology. 10 and 3% were perforated and gangrenous appendix. Only 6% were normal. Sensitivity and specificity of leukocyte count was 77.5 and 63.6%, C-reactive protein was 88.8 and 72.4% and serum bilirubin was 89.9 and 81.8% respectively. In addition to clinical and radiological examination, laboratory test are definitely helpful in diagnosing acute appendicitis. Serum bilirubin is more suitable parameter in diagnosing appendicitis than C-reactive protein and TLC.
Keywords: Total leukocyte count, serum bilirubin, C-reactive protein
Cite this Article:
Kapil Beniwal, Satyendra Pal Singh. Study of Leucocyte Count, Serum Bilirubin and C-Reactive Protein Values in Preoperative Diagnosis of Acute Appendicits. Research & Reviews: Journal of Surgery. 2015; 4(1): 20–26p.
Downloads
Published
Issue
Section
License
Declaration and Copyright Transfer Form
(to be completed by authors)
I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.
- I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.
- I/We Author(s ) have neither given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).
- I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.
- I/We also agree to the authorship of the article in the following order:
Author’s name
1. ________________
2. ________________
3. ________________
4. ________________
| We Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal. |
