Analysis of Transdermal Patches: A Surgical Perspective

Abstract

In addressing the challenges associated with oral drug administration, the introduction of a transdermal drug delivery system has proven to be a valuable alternative. This system involves the application of a transdermal patch onto the skin, facilitating the controlled release of a specific medication through the skin and into the bloodstream. The primary objective is to enhance the healing process of the affected area of the body. Notably, the transdermal route offers distinct advantages over other delivery methods, including oral, topical, intravenous, and intramuscular administration. A noteworthy benefit of the transdermal drug delivery system lies in its ability to ensure a controlled and sustained release of medication within the patient's body. However, it is essential to acknowledge certain limitations associated with this approach. Drugs characterized by hydrophilic structures may exhibit slow penetration through the skin, potentially hindering the attainment of therapeutic levels. Additionally, there is a risk of local skin reactions, such as redness, itching, and swelling, attributed to the drug itself, adhesive, or other excipients present in the patch. This comprehensive review aims to provide a thorough understanding of transdermal patches, encompassing their mechanisms, advantages, and limitations. By delving into the intricacies of this drug delivery system, the study contributes to the broader knowledge base, facilitating a nuanced appreciation of the potential and challenges associated with transdermal drug delivery. As researchers continue to explore innovative solutions, the field holds promise for refining this delivery method and expanding its applications in the realm of healthcare.