Guidelines for Management of Post Lymphedema Nonhealing Ulcer of Lower Limb
DOI:
https://doi.org/10.37591/rrjot.v13i3.3425Keywords:
Lymphedema, guidelines, management, diagnosis, lymphatic fluidAbstract
Lymphedema represents a widespread medical concern, affecting a staggering 140.2 million individuals globally; however, its status as a vascular disease often remains underappreciated. In contrast to arterial and venous diseases, which have witnessed advancements in diagnostic and therapeutic approaches with the formulation of clinical practice guidelines (CPGs), lymphedema faces a conspicuous dearth of such comprehensive guidance. Despite the significant global prevalence of lymphedema, the lack of wellestablished guidelines has impeded standardized and effective management strategies. Moreover, the efficacy of clinical practice guidelines hinges on their quality and development through meticulous evidence-based methodologies. Recognizing this critical aspect, ourstudy delves into a systematic review of the currently available CPGs for lymphedema. Our objective is to assess the comprehensiveness and methodological robustness of these guidelines, aiming to identify gaps and potential areas for enhancement in the clinical management of this condition. By scrutinizing existing CPGs, we aim to contribute valuable insights that can guide future developments in lymphedema care. This research initiative addresses the pressing need for standardized and evidence-based approaches in the diagnosis and treatment of lymphedema, aligning with the trajectory of advancements witnessed in other vascular diseases. Through our systematic evaluation, we aspire to catalyze improvements in the understanding and management of lymphedema, ultimately enhancing the overall quality of care for the vast number of individuals affected by this often-overlooked vascular condition.References
Rockson SG, Rivera KK. Estimating the population burden of lymphedema. Ann N Y Acad Sci.
; 1131: 147–154.
DiSipio T, Rye S, Newman B, Hayes S. Incidence of unilateral arm lymphoedema after breast
cancer: a systematic review and meta-analysis. Lancet Oncol. 2013; 14 (6): 500–515
Ridner SH, Dietrich MS, Niermann K, Cmelak A, Mannion K, Murphy B. A prospective study of
the lymphedema and fibrosis continuum in patients with head and neck cancer. Lymphat Res Biol.
; 14 (4): 198–205.
Hayes SC, Janda M, Ward LC, Reul-Hirche H, Steele ML, Carter J, Quinn M, Cornish B, Obermair
A. Lymphedema following gynecological cancer: Results from a prospective, longitudinal cohort
study on prevalence, incidence and risk factors. Gynecol Oncol. 2017; 146 (3): 623–629.
Andraska EA, Horne DC, Campbell DN, Eliason JL, Wakefield TW, Coleman DM. Patterns of
pediatric venous disease. J Vasc Surg Venous Lymphat Disord. 2016; 4 (4): 422–425.
Cazzolla AP, Lo Muzio L, Di Fede O, Lacarbonara V, Colaprico A, Testa NF, Giuseppe T,
Zhurakivska K, Marzo G, Lacaita MG. Orthopedic-orthodontic treatment of the patient with
Turner s syndrome: review of the literature and case report. Spec Care Dentist. 2018; 38 (4): 239–
Slater HC, Gambhir M, Parham PE, Michael E. Modelling co-infection with malaria and lymphatic
filariasis. PLoS Comput Biol. 2013; 9 (6): e1003096.
Grada AA, Phillips TJ. Lymphedema: Pathophysiology and clinical manifestations. J Am Acad
Dermatol. 2017; 77 (6): 1009–1020.
King B. Diagnosis and management of lymphoedema. Nurs Times. 2006; 102 (13): 47, 49, 51.
Mortimer PS. Swollen lower limb – 2: lymphoedema. BMJ. 2000; 320 (7248): 1527–1529.
Lund E. Exploring the use of CircAid legging in the management of lymphoedema. Int J Palliat
Nurs. 2000; 6 (8): 383–391.
Greene AK, Goss JA. Diagnosis and staging of lymphedema. Semin Plast Surg. 2018; 32 (1): 12–
Maclellan RA, Greene AK. Lymphedema. Semin Pediatr Surg. 2014; 23 (4): 191–197.
Biglia N, Zanfagnin V, Daniele A, Robba E, Bounous VE. Lower body lymphedema in patients
with gynecologic cancer. Anticancer Res. 2017; 37 (8): 4005–4015.
Getz DH. The primary, secondary, and tertiary nursing interventions of lymphedema. Cancer Nurs.
; 8 (3): 177–184.
Warren AG, Brorson H, Borud LJ, Slavin SA. Lymphedema: a comprehensive review. Ann Plast
Surg. 2007; 59 (4): 464–472.
Granzow JW. Lymphedema surgery: the current state of the art. Clin Exp Metastasis. 2018; 35 (5–
: 553–558.
Lee M, Perry L, Granzow J. Suction assisted protein lipectomy (SAPL) even for the treatment of
chronic fibrotic and scarified lower extremity lymphedema. Lymphology. 2016; 49 (1): 36–41.
Tiwari A, Cheng KS, Button M, Myint F, Hamilton G. Differential diagnosis, investigation, and
current treatment of lower limb lymphedema. Arch Surg. 2003; 138 (2): 152–161.
Bardare M, Falcini F, Hertzberger-ten Cate R, Savolainen A, Cimaz R. Idiopathic limb edema in
children with chronic arthritis: a multicenter report of 12 cases. J Rheumatol. 1997; 24 (2): 384–
De Backer D, Creteur J, Dubois MJ, Sakr Y, Koch M, Verdant C, Vincent JL. The effects of
dobutamine on microcirculatory alterations in patients with septic shock are independent of its
systemic effects*. Critical Care Medicine. Feb 2006; 34(2): 403-408. DOI:
1097/01.CCM.0000198107.61493.5A.
Farhat MM, Le Guern A, Peugniez C, Dabouz F, Quinchon JF, Modiano P. Angiosarcoma in
primary lymphoedema: a rare complication. Ann Dermatol Venereol. 2018; 145 (4): 266–269.
Downloads
Published
Issue
Section
License
Declaration and Copyright Transfer Form
(to be completed by authors)
I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.
- I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.
- I/We Author(s ) have niether given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).
- I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.
- I/We also agree to the authorship of the article in the following order:
Author’s name
1. ________________
2. ________________
3. ________________
4. ________________
| We Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal. |
