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Clinical Study for Evaluation of Comprehensive Ayurvedic Management in Nicotine Use Disorder

Rishu Sharma, Gyanendra Datta Shukla

Abstract


Substance use disorder (SUD), is a condition in which the use of one or more substances leads to a clinically significant impairment or distress. 'Substance' in this clinical study is limited to nicotine-based substances (Nicotine Use Disorder). This study evaluates the effect of Ayurvedic management on Nicotine Use Disorder. 36 Patients were registered in this study having signs and symptoms of nicotine use disorder and were treated with Ayurvedic management for a period of twelve weeks that includes Nasya Karma (errhine therapy) Shamana drug (self-made powdered Ayurvedic formulation) and Satvaavjaya Chikitsa (Behavioral and Psychological Therapy). Diagnostic criterion taken into consideration was Fagerstrom Test for Nicotine Dependence (FTND) and psychometric parameters; Hamilton Anxiety Rating Scale (HARS) and Hamilton Depression Rating Scale (HDRS) were also taken into consideration before and after completion of trial. Ashta Manas Pareekshya Bhavas were also taken into account for analysis of results. Statistical analysis was performed by using Wilcoxon Signed Rank Test. Statistically highly significant results (P< 0.001) were obtained in all the parameters. The results indicate that comprehensive Ayurvedic management has significant result in the management of Nicotine Use Disorder.


Keywords


Nasya Karma, Nicotine Use Disorder, Satvaavjaya Chikitsa, Substance Use Disorder

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References


Diagnostic and statistical manual of mental disorders (5 ed.). Arlington, VA: American Psychiatric Association. 2013. 483p.

The MPOWER package, warning about the dangers of tobacco. Geneva: WHO; 2011. WHO Report on The Global Tobacco Epidemic, 2011.

Jha P, Jacob B, Gajalakshmi V, et al. A nationally representative case–control study of smoking and death in India. N Engl J Med. 2008; 358: 1137–47p.

Jha P Jacob B, Gajalakshmi V, et al. Tobacco addiction. In: Jamison DT, et al., eds. Disease control priorities in developing countries, 2nd ed. New York, NY, Oxford University Press, 2006, 869–886p.

WHO report on the global tobacco epidemic: implementing smoke-free environments, Geneva, World Health Organization, 2009.

Lynch B, Bonnie RJ, eds. Growing up tobacco free: preventing nicotine addiction in children and youths. Institute of Medicine Committee on Preventing Nicotine Addiction on Children and

Youths. Washington, DC, National Academy Press, 1994.

Karan LD, Dani JA, Benowitz NL. The pharmacology of nicotine dependence. In: Principles of addiction medicine, 3rd ed. Washington, DC, American Society of Addiction Medicine, 2003: 225–248p.

Jarvis MJ. ABC of smoking cessation: why people smoke. Brit Med J. 2004; 328: 277–279p.

Tobacco smoking in Britain: an overview. In: Nicotine addiction in Britain: report of the Tobacco Advisory Group of the Royal College of Physicians. London, Royal College of Physicians, 2000.

Hendricks S, et al. The early time course of smoking withdrawal effects. Psychopharmacology. 2006, 187: 385–396p.

Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom KO. The Fagerstrom Test for Nicotine Dependence: a revision of the Fagerstrom Tolerance Questionnaire. Br J Addict. 1991; 86: 1119–27p.

Myers MG. Smoking intervention with adolescent substance abusers: Initial recommendations. J Subst Abuse Treat. 1999; 16: 289–298p.

Acharya Kaviraj Ambika Dutta Shastri, A.M.S, editor. Sushruta Samhita of Sushruta with Ayurveda Tattva Sandipika, Sutra Sthana, Ch.15, Ver.48. Varanasi: Chaukhambha Surbharati Prakashan; 2014. 800p.

Acharya Yadavji Trikamji, editor. Charaka Samhita of Agnivesha with Ayurveda Deepika commentary of Chakrapani Datta, Vimana Sthana. Ch. 06, Ver.5, Reprint edition. Varanasi: Chaukhambha Prakashan; 2011. 254p.

Vaidya Yadavji Trikamji Acharya, Charaka Samhita of Charaka, Ayurveda Deepika Teeka of Chakrapani, Reprint ed. Varanasi: Chaukhambha Sanskrit Sansthan; 1994. 4th edition. 468p.

Vaidya Yadavji Trikamji Acharya, Charaka Samhita of Charaka, Ayurveda Deepika Teeka of Chakrapani, Reprint ed. Varanasi: Chaukhambha Sanskrit Sansthan; 1994. 4th edition. 223p.

Saraf MK, Prabhakar S, Anand A. Neuroprotective effect of Bacopa monniera on ischemia induced brain injury. Pharmacol Biochem Behav. 2010; 97: 192–7p.

Pathak SR. A neuro humoral study on brain function in stress anti-stress drug with special reference to the effect of some plant product. [Ph.D. Thesis]. Varanasi: Banaras Hindu University; 1990.

Manyam BV. Dementia in Ayurveda. J Altern Complement Med. 1999; 5: 81–8p.

Khare CP. Indian Medicinal Plants an Illustrated Dictionary. Heidelberg: Springer-Verlag; 2007.

Colmers WF. Modulation of synaptic transmission in hippocampus by neuropeptide Y: Presynaptic actions. Ann N Y Acad Sci. 1990; 611: 206–18p.

Oh MH, Houghton PJ, Whang WK, Cho JH. Screening of Korean herbal medicines used to improve cognitive function for anti-cholinesterase activity. Phytomedicine. 2004; 11: 544–8p.

Chandre R, Narasimha Murthy VSSS, Singh RH. Evaluation of the efficacy of kushmandaghrta in the management of

depressive illness. Aryavaidyan. 2004; 18: 87–90p.

Weiss R.F. Herbal Medicine. Gothenberg, Sweden: Ab Arcanum; and Beaconsfield, UK: Beaconsfield Publishers, 1985, 44–46p.

Charness ME, Simon RP, Greenberg DA. Ethanol and the nervous system. N Engl J Med. 1989; 321: 442–54p.

Acharya Yadavji Trikamji, editor. Charaka Samhita of Agnivesha with Ayurveda Deepika commentary of Chakrapani Datta, Sutra Sthana. Ch. 11, Ver.54, Reprint edition. Varanasi, Chaukhambha Prakashan; 2011. 231p.


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