Toxic Epidermal Necrolysis Induced by Diclofenac Sodium in a Dental Patient: A Case Report

Authors

  • Deep Inder
  • Pawan Kumar
  • Geeta Mourya
  • Praveen Kumar

DOI:

https://doi.org/10.37591/rrjod.v4i1.1061

Abstract

Diclofenac sodium is a widely prescribed non-steroidal anti-inflammatory drug in dental practice. Propionic acid derivatives and oxicams have been reported to be associated with erythema multiforme and Steven-Johnson syndrome. Here the authors present a rare case report of toxic epidermal necrolysis (TEN) induced by diclofenac sodium. The patient presented in dental clinic with toothache for which planned tooth extraction was done under antibiotic cover. Post extraction, patient was prescribed diclofenac sodium (50 mg b.i.d) for 3 days. The patient reported with generalized pruritic rashes with exfoliated skin to the extent of > 25%. Diclofenac was stopped promptly. The clinical condition of patient was monitored and multidisciplinary management was done to tackle emergency. No rechallenge was given. Although diclofenac sodium-induced TEN is a rare adverse effect, physicians and dentists must be careful prescribing diclofenac due to its life threatening adverse drug effect.

 

Keywords: Diclofenac, toxic epidermal necrolysis, adverse effects 

Downloads

Published

2019-03-28

Issue

Vol. 4 No. 1 (2013)

Section

Case Study

License

Declaration and Copyright Transfer Form

(to be completed by authors)

I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.

  • I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.
  • I/We Author(s ) have niether given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).
  • I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.
  •  I/We also agree to the authorship of the article in the following order:

Author’s name                                    

 

1. ________________

2. ________________

3. ________________

4. ________________

 

We  Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal.