Summer Outbreak of Influenza A (H1N1) at Tertiary Care Centre in Central India

Abstract

Background: Influenza is a highly contagious, acute, and febrile respiratory illness that occurs in epidemics and occasionally in pandemics. Post-pandemic resurgence with bi-modal peaks, a major peak in the rainy season, and a minor peak in the winter-spring season have been reported in India. However, a sudden increase in the number of cases of Influenza-like illness (ILI) was observed at our centre during the summer season. The study was conducted to confirm the aetiology and distribution of cases of ILI. Material and Methods: Nasal and throat swabs were collected from ILI cases reporting in-patient department and were tested by real-time RT-PCR. Results: Out of 447 patients with ILI 101(22.59%) were positive for Influenza A (H1N1). Maximum (26.73%) Influenza activity was seen in 21–30 years of age group. Females (59.41%) were affected more than males (40.59%). A most common presenting feature was fever followed by nasal discharge, cough, chills and rigours and sore throat. Diabetes (11.88%) and anaemia (10.89%) were the most common medical ailments associated with H1N1 infection. 27.72% had either history of travel to swine flu (H1N1) infected area or contact with swine flu infected patient. Influenza activity was found to have a positive correlation with the increase in temperature and decrease in humidity. Conclusion: H1N1 transmission activity has increased and the need of the hour is to undertake continued surveillance globally to define the circulation of influenza viruses.

Keywords: H1N1, influenza, summer outbreak, RT-PCR

Cite this Article

Smita Deshkar, Ravindra Khadse, Sharmila Raut. Summer Outbreak of Influenza A (H1N1) at Tertiary Care Centre in Central India. Research & Reviews: A Journal of Immunology. 2018; 8(3): 24–31p.