Molecular Identification of Common Bacterial Infection in Chronic Otitis Media in an Outpatient Department of Tertiary Care Hospital

Abstract

Chronic otitis media (COM) is a chronic inflammation of the mucoperiosteum of the middle ear left which leads to profuse discharge from the ear and hearing impairment that may have a serious long-term effect on language, auditory and cognitive development and on educational progress. In the present study, the prevalence of culture-positive cases of an active mucosal variety of COM was 92.65%. Pseudomonas aeruginosa (41.2%) was the predominant aerobic bacterial etiology of COM followed by Staphylococcus aureus (38%) in this region. The isolates were identified by both biochemical methods and molecular methods. Aminoglycosides were found to be much more effective against P.aeruginosa and S. aureus. The isolates were found to be resistant to the drugs which are frequently used in the hospitals such as ceftriaxone, cefpodoxime, cefuroxime, amoxicillin and azithromycin. Commonly available antibiotics such as ofloxacin, levofloxacin, ciprofloxacin and gentamicin showed good activity for most of the commonly isolated organisms. This study reveals that the irrational use of antibiotics should be avoided. Moreover, this data can be used for the treatment of other patients. An effective antibiotic policy can also be made from this data. We believe that this study will contribute to the effective management of an active mucosal variety of COM.

Keywords: Bacterial infection, molecular identification, Staphylococcus aureus, chronic otitis media (COM), Pseudomonas aeruginosa

Cite this Article

Tanvi Choubey Varsha Rani Gajamer Arunabha Sarkar et al. Molecular identification of common bacterial infection in chronic otitis media in an outpatient department of tertiary care hospital. Research & Reviews: Journal of Medical Science and Technology. 2019; 8(1): 18–24p.