Review on Optic Atrophy
Keywords:
Optic atrophy, ischemic optic neuropathy, nerve disease, glaucoma, peripheral visionAbstract
The illness known as otic atrophy damages the eye. It causes anterior ischemic optic neuropathy, also known as glaucoma, and strokes of the optic nerve. A change in vision, notably blurred vision, problems with peripheral (side) vision, problems with color vision, and a loss of vision sharpness, are indications of optic atrophy. The final stage of a disease process that affects the retinogeniculate section of the visual pathway is called optic atrophy, and it is identified by the non-specific symptom of optic disc pallor. As a result, rather than acting like a real peripheral nerve, the optic nerve, with its 1.2 million fibers, functions more like a white matter tract. Pial capillaries that supply the optic nerve head experience degeneration, which contributes to the pallor of the optic disc seen in optic atrophy.
References
Golnik K. Nonglaucomatous optic atrophy. Neurol Clin. 2010; 28 (3): 631–640. doi: 10.1016/j.ncl.2010.03.005, PMID 20637993.
Li H-J, Sun Z-L, Yang X-T, Zhu L, Feng D-F. Exploring optic nerve axon regeneration. Curr Neuropharmacol. 2017; 15 (6): 861873. doi: 10.2174/1570159X14666161227150250.
Quigley HA, Anderson DR. The histologic basis of optic disk pallor in experimental optic atrophy. Am J Ophthalmol. 1977; 83 (5): 709–717. doi: 10.1016/0002-9394(77)90138-6.
Yu-Wai-Man P, Turnbull DM, Chinnery PF. Leber hereditary optic neuropathy. J Med Genet. 2002; 39 (3): 162–169. doi: 10.1136/jmg.39.3.162, PMID 11897814.
Barrow Neurological Institute. (2022). Traumatic optic neuropathy. [Online] Available at https://www.barrowneuro.org/condition/traumatic-optic-neuropathy/ [Accessed on July 2023]
Tonari M, Matsuo J, Hidehiro JS, Tsunehikolkeda KT, Fujita T, Tatsuzawa K et al. A case of childhood-onset giant cell tumor that caused optic nerve atrophy in both eyes. Case Rep Ophthalmol. 2017; 8 (2): 301–307. doi: 10.1159/000477199, PMID 28626415.
Cleveland Clinic. (2015). Optic atrophy. [Online]. Available at https://my.clevelandclinic.org/health/diseases/12326-optic-atrophy [Accessed on July 2023]
FitzGibbon EJ, Wendt S. (2023). Optic atrophy. [Online] Aao.org. Available at https://eyewiki.aao.org/Optic_Atrophy [Accessed on July 2023]
Venkatramani DV, Amula GM, Gandhi RA. Optic atrophy: major review. Kerala J Ophthalmol. 2010; [Online] Available at https://www.scribd.com/document/261554682/Optic-Atrophy-major- review-March-2010-Kerala-Journal-of-Ophthalmology-Devendra-V-Venkatramani-et-al#.
Eye Cure Center. (2019). Eye cure center. [Online] Eyecurecenter.org. Available at https://www.eyecurecenter.org/ [Accessed on July 2023]
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