Anti-Diarrhoeal Effects of Probiotics on Children
Abstract
Diarrhoeal disease is one of the major problems among under-five year children in Bangladesh. Probiotics have been suggested to be used in acute diarrhoea. Several different probiotics are commercially available in our country. The objective of this experimental study was to assess the effects of probiotics among under-five year children suffering from diarrhoea. This study was conducted using probiotics with oral rehydration solution (ORS) and ORS only which were given to the children for the treatment of acute diarrhoea. It was conducted using three probiotics namely, Probio, Enterogermina, and TS6 with ORS only (control group) among one hundred and sixty under-five children admitted to Chittagong Maa-Shishu General Hospital in Chittagong, Bangladesh. Children were divided into group 1, received ORS only and group 2, group 3, group 4, received Probio, Enterogermina, TS6 probiotics with ORS, respectively. The duration of diarrhoea and daily stool outputs of children was recorded during hospitalization. The study showed that three probiotics had significantly reduced the frequency of diarrhoea of children than ORS only. Three probiotics had significant or positive effect on children with acute diarrhoea resulting in shorter (P <0.001) duration of diarrhoea (hours).
Keywords: Diarrhoeal diseases, children, probiotics, oral rehydration solution (ORS)
Cite this Article Akter S, Aziz MA, Sharmin KN et al. Anti-Diarrhoeal Effects of Probiotics on Children. Research & Reviews: A Journal of Microbiology and Virology. 2018; 8(1): 15–21p.
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Paraschiv D, Vasile A, Constantin M, et al . Study of physiological properties of some probiotics in multiple cultures with mesophilic lactic acid bacteria by flora danica ch. hansen commercial starter. The Annals of the University of Dunarea de Jos of Galati. Fascicle VI. Food Technology. 2011; 35(2):56p.
Metchnikoff E, MITCHELL SP. The Prolongation of Life: optimistic studies... The English translation edited by P. Chalmers Mitchell. London; 1907
Lilly DM, Stillwell RH. Probiotics: growth-promoting factors produced by microorganisms. Science. 1965; 147(3659):747-8p.
Allen SJ, Okoko B, Martinez E, et al. Probiotics for treating infectious diarrhoea. Cochrane Database Syst Rev. 2003;4.
Alam NH, Ashraf H. Treatment of infectious diarrhea in children. Pediatric Drugs. 2003; 5(3):151-65p.
Guarino A, Canani RB, Spagnuolo MI, et al. Oral bacterial therapy reduces the duration of symptoms and of viral excretion in children with mild diarrhea. Journal of pediatric gastroenterology and nutrition. 1997; 25(5):516-9p.
Zimmerman CM, Bresee JS, Parashar UD, et al. Cost of diarrhea-associated hospitalizations and outpatient visits in an insured population of young children in the United States. The Pediatric infectious disease journal. 2001; 20(1):14-9p.
Rosenfeldt V, Vesikari T, Pang XL, et al . Viral etiology and incidence of acute gastroenteritis in young children attending day-care centers. The Pediatric infectious disease journal. 2005; 24(11):962-5p
Young J. European market developments in prebiotic-and probiotic-containing foodstuffs. The British journal of nutrition. 1998 ;80(4):S231-3.
De Vecchi E, Drago L. Lactobacillus sporogenes or Bacillus coagulans: misidentification or mislabelling?. international Journal of Probiotics and Prebiotics. 2006;1(1):3-10p.
Chouraqui JP, Van Egroo LD, Fichot MC. Acidified milk formula supplemented with Bifidobacterium lactis: impact on infant diarrhea in residential care settings. Journal of pediatric gastroenterology and nutrition. 2004; 38(3):288-92p.
Thibault H, Aubert-Jacquin C, Goulet O. Effects of long-term consumption of a fermented infant formula (with Bifidobacterium breve c50 and Streptococcus thermophilus 065) on acute diarrhea in healthy infants. Journal of pediatric gastroenterology and nutrition. 2004; 39(2):147-52p.
Weizman Z, Asli G, Alsheikh A. Effect of a probiotic infant formula on infections in child care centers: comparison of two probiotic agents. Pediatrics. 2005; 115(1):5-9p.
Simakachorn N, Pichaipat V, Rithipornpaisarn P, et al. Clinical evaluation of the addition of lyophilized, heat-killed Lactobacillus acidophilus LB to oral rehydration therapy in the treatment of acute diarrhea in children. Journal of pediatric gastroenterology and nutrition. 2000; 30(1):68-72p.
Szajewska H, Setty M, Mrukowicz J, et al . Probiotics in gastrointestinal diseases in children: hard and not-so-hard evidence of efficacy. Journal of pediatric gastroenterology and nutrition. 2006; 42(5):454-75p.
Sazawal S, Hiremath G, Dhingra U, et al . Efficacy of probiotics in prevention of acute diarrhoea: a meta-analysis of masked, randomised, placebo-controlled trials. The Lancet infectious diseases. 2006; 6(6):374-82p.
Guandalini S, Pensabene L, Zikri MA, et al . Lactobacillus GG administered in oral rehydration solution to children with acute diarrhea: a multicenter European trial. Journal of pediatric gastroenterology and nutrition. 2000 ;30(1):54-60p.
DOI: https://doi.org/10.37591/rrjomv.v8i1.171
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