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Chronic Renal Failure: A General Review

Gyanendra kumar Gupta, Gagan Devi


Chronic renal failure is also known as chronic kidney disease in which there is progressive loss in kidney function over a period of months or years. The symptoms of worsening kidney function are not specific and might include feeling generally unwell and experiencing a reduced appetite. The definition of chronic kidney disease has been simplified over the last 5 years. It is now defined as the presence of kidney damage for a period greater than 3 months. An estimated or measured glomerular filtration rate of less than 60 ml/min/1.73 m2 is considered abnormal for all adults. Chronic renal failure is reported to be a silent epidemic disease. CRF is unique amongst the chronic non-infectious illness.


Chronic renal failure,Chronic kidney disease, Glomerular Filtration,Epidemic disease and Appetite

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Wikipedia. Chronic kidney disease. (Archieved:2013-03-15). Available Online at:

Adeera Levin, Brenda Hemmelgarn, et al, Guidelines for the management of chronic kidney disease, CMAJ. 2008 Nov 18; 179(11): 1154–1162.

Madhumathi Rao & Brian J.G. Perera: Chronic kidney disease in India- a hidden epidemic: Indian J Med Res. 2007 Jul;126(1):6-9.

Sneha Aswale, A case discussion on CRF (mūtrāghāta) treated with kṣāra basti and māṁsa rasa basti, IJAAM, vol 3(1)2015, eISSN,2348-0173

National kidney foundation (2002). "K/DOQI clinical practice guidelines for chronic kidney disease". Retrieved 2008-06-29. Available online at:

Brian R. Walker, Nicki R. College, Stuart H. Ralston, Ian D. Penman, Davidson‘s principles & practice of medicine, 22nd Edition, page no-483.

7.Gupta Mahesh Chand, Trilok chand, a critical review on commonly used herbal drugs in CKD, JMPS,2015:3(4):44-47

Shamsuddin N, Gnanasan S, Karuppanan Mand Farooqui M, Complementary and alternative medicine (CAM) in chronic kidney disease(CKD) more evidence needed, Altern Integr Med 2016:5(4). DOI: 10.4172/2327-5162.1000223,October 16,2016

Yadav Ritu, J.P.Singh, Sahu Ajay Kumar, Sharma Pankaj, Management of chronic kidney disease in Ayurvedic setting: a case report, IJAAR. 2017:2(11) ISSN 2347-6362.

Ajay K Singh, et al., Epidemiology and risk factors of chronic kidney disease in India – results from the SEEK (Screening and Early Evaluation of Kidney Disease) study, BMC Nephrology Article number: 114 (2013).

Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, Van Lente F, Levey AS. Prevalence of chronic kidney disease in the United States. 2007 Nov 7;298(17):2038-47.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases. U.S. Renal Data System Report. Available online at:

Master Pathophysiology Review. Chronic Kidney Disease (CKD). Available online at:



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