Isolation and Identification of Bacteria Causing Chronic Suppurative Otitis Media and Its Antibiogram

Abstract

Background: Chronic Suppurative Otitis Media (CSOM) is defined as chronic inflammation of middle ear and mastoid cavity, which presents with recurrent ear discharge or otorrhoea through a tympanic perforation. According to WHO, the prevalence of CSOM in India is more than 4% and it falls among those countries where urgent attention is needed. It can be caused by various bacteria, fungus and viruses. Bacterial origin of CSOM is more common than other etiologies. Aims and Objectives: The present study is aimed to detect common organisms which are responsible for CSOM, most common organism responsible for the complications and to determine the antibiotic sensitivity pattern of the organisms isolated from CSOM. Results: Ear swabs were taken from 100 clinically diagnosed cases of CSOM attending department of ear, nose and throat, MBS hospital and NMCH and were subjected to culture and antibiotic susceptibility. 104 (88.13%) among 118 ear swabs from total 100 patients were culture positive and 14 (11.87%) were culture negative. The most frequently isolated organisms in CSOM patients were Pseudomonas aeruginosa (42 (40.38%)), followed by Staphylococcus aureus (36 (34.6%)), Klebsiella pneumoniae (12 (11.53%)), Escherichia coli (08 (7.69%)) and Proteus mirabilis (06 (5.76%)). Most effective and favorable drug in our study for Pseudomonas aeruginosa was piperacillin-tazobactum, followed by cefepime. Staphylococcus aureus were 100% sensitive to Vancomycin and Linezolid, and 61.11% were MRSA. Conclusion: This study highlights the need for active diagnosis and management of CSOM. Judicious use of antibiotics is recommended and also the patient must complete a course of treatment as prescribed, because inadequate treatment may cause the emergence of resistant microorganisms.

Keywords: CSOM, bacterial, gram positive, gram negative

Cite this Article
Anita E. Chand, Charu Sharma. Isolation and Identification of Bacteria Causing Chronic Suppurative Otitis Media and Its Antibiogram. Research & Reviews: A Journal of Microbiology and Virology. 2019; 9(3): 1–5p.