A Unique Insight on Detoxification and Inactivation of Metal Toxicity in Herbal-Metal Preparations in Siddha System
Keywords:
Metal chelating, herbal, toxicity, SiddhaAbstract
Metal chelating property of various time tested siddha herbs were tested individually vis a vis Phyllanthus emblica, Embelia ribes, Elettaria cardamomum, Withania somnifera, Corollocarpus epigaeus, Centella asiatica, Celastrus paniculatus, Smilax chinensis, Psoralea corylifolia, Solanum trilobatum and Indigofera aspalathoides. Most of the plants showed metal chelating effect suggesting their role in in-activating metal toxicity. Use of these herbs along with metal preparation may offer some value in reducing toxicity due to heavy metalsReferences
Gogtay NJ, Bhatt HA, et al. The Use and Safety of Non-Allopathic Indian Medicines. Drug safety. 2002; 25(14): 1005–1019p.
Bharti SK, Singh SK. Metal Based Drugs: Current Use and Future Potential, Der Pharmacia Lettre. 2009; 1 (2): 39–51p.
Kapoor RC. Some Observations on the Metal-based Preparations in the Indian Systems of Medicine. Indian J Traditional Knowl. 2010; 9(3): 562–575p.
Anand Chaudhary, Neetu Singh. Herbo Mineral Formulations (Rasaoushadhies) of Ayurveda an Amazing Inheritance of Ayurvedic Pharmaceutics. Ancient Sci Life. 2010; 30(1): 18–26p.
Mahalakshmi G, Sathish Raja, et al. Quality Assesment of a Traditional Siddha Drug “Mupoora Chendrum”. Am J Phytomed Clin Therap. 2015; 2(5): 571–579p.
Mohammad Ali Ebrahimzadeh, Fereshteh Pourmorad, Ahmad Reza Bekhradnia. Iron Chelating Activity, Phenol and Flavonoid Content of Some Medicinal Plants from Iran. Afr J Biotechnol. 2008; 7(18): 3188–3192p.
Riddhi M. Patel. Ferrous Ion Chelating Activity (FICA)- A Comparative Antioxidant Evaluation of Extracts of Eleven Naturally Growing Plants of Gujarat, India. Int J Sci Res. 2013; 2(8): 2277–8179p.
Ilanchezhian R, Roshy Joseph C, Rabinarayan Acharya. Importance of Media in Shodhana (Purification/Processing) of Poisonous Herbal Drugs. Ancient Sci. Life. 2010; 30(2): 54–57p.
Mradu Gupta, Shaw BP. Use of Medicinal Plants in Panchakarma Ayurvedic Therapy. Indian J Traditional Knowl. 2009; 8(3): 372–378p.
Reena Singh, Neetu Gautam, Anurag Mishra, et al. Metals and Living Systems: An Overview. Indian J. Pharmacol. 2011; 43(3): 246–253p.
Olena K. Vatamaniuk, Elizabeth A. Bucher, et al. A New Pathway for Heavy Metal Detoxification in Animals Phytochelatin Synthase is required for Cadmium Tolerance in caenorhabditis elegans. J Biol Chem. 2001; 276(24): 20817–20820p.
Robert E. Herron, PhD, John B. Fagan. Lipophil-Mediated Reduction of Toxicants in Humans: An Evaluation of An Ayurvedic Detoxification Procedure. Altern Therap. 2002; 8(5): 40–51p.
Khan KH. Roles of Emblica Officinalis in Medicine - A Review. Bot Res Int. 2009; 2(4): 218–228p.
Lakshmi-Chandra Mishra, et al. Scientific Basis for the Therapeutic Use of Withania somnifera (Ashwagandha): A Review. Altern Med Rev. 2000; 5(4): 334–346p.
By David Frawley, Vasant Lad. The Yoga of Herbs: An Ayurvedic Guide to Herbal Medicine. Lotus Press, USA, 2004, 44p.
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