Operational Research—Tuberculosis Overview

Authors

  • M. Manasa Rekha Dr Mekkanti Manasa Rekha Pharm.D,RCPh,(Ph.D),FSASS Assistant Professor & Scientist Department of Pharmacy Practice,Gautham College of Pharmacy,Bangalore,Karnataka,India. Research Scholar in MSRUAS
  • Mohammed Hassain Majid Khan
  • Allah Ifatha Mariayam
  • Tasmiya Sultana
  • Nesson Rajan
  • Shabaz Pasha

Keywords:

Operational research, tuberculosis, India, COVID-19, communicable diseases

Abstract

The present review outlined the basic information regarding operational research for successful control of communicable diseases in India with its history of origin, objectives, scope, basic approaches, steps, and principles involved. Also the descriptive critical review on burden of communicable diseases such as tuberculosis and COVID-19 burden in India along with present scenario and problems being faced by India over control of communicable diseases in 2020 were also discussed. The present review covered all the possible information regarding operational research which is a distinctive instrument leading to greater benefits for the epidemiologists, health policymakers, health economists, public health specialists to get solutions for the problems and to develop effective methods to solve the problems in timely manner for the relevant problems in public health system, particularly for effective control of communicable diseases.

Author Biography

  • M. Manasa Rekha, Dr Mekkanti Manasa Rekha Pharm.D,RCPh,(Ph.D),FSASS Assistant Professor & Scientist Department of Pharmacy Practice,Gautham College of Pharmacy,Bangalore,Karnataka,India. Research Scholar in MSRUAS

    Dr. Mekkanti Manasa Rekha Pharm.D, RCPh, [PhD],FSASS has been awarded with many awards like Outstanding Scientist, Best Scientist and Young Scientist, Best Researcher awards, Best Women Scientist, Best Senior Scientist, Young Researcher etc., respectively in the field of Research on Public Health and related Projects in Hospitals and under the Department of Pharmacy Practice and a registered PhD (Doctor of Philosophy) Research Scholar in M.S. Ramaiah University of Applied Sciences Bangalore Karnataka India (UGC Approved Accredited by NAAC, Recognized By ICARE rating by KSURF, KSHEC-Government of Karnataka, NIRF-MHRD, ARIIA, Indian University GOLD ranking by QS-I.GAUGE).Currently working as Assistant Professor in Department of Pharmacy Practice, Gautham College of Pharmacy Bangalore Karnataka India. Completed Pharm.D Topper and Gold Medalist during her Pharm.D course of study at Annamacharya College of Pharmacy, Rajampet, YSR Kadapa District, Andhra Pradesh, India (Accredited by NAAC with “A” grade, accredited by NBA(UG),New Delhi, recognized u/s2(f)&12-b of the UGC act,1956,affiliated to JNTUA, Ananthapuramu, approved by AICTE, PCI, New Delhi, recognized research centre by JNTUA) Working as  Professional Life  Member in various Research councils across worldwide Completed PHARM-D  and Topper and Gold Medalist  during Pharm.D course study (2011-2017 Batch)  at Annamacharya College of Pharmacy and Participated  110 National, International Conferences, U.G.C sponsored  Workshops, Webinars, Essay Competitions, Science Fares and Quiz Competitions ,Talent search examinations and Achieved 65 prizes and have Published 150 Research and Review papers in various National and International Journals with good impact factors and got 4 Best Speaker Awards in World Scientific Congresses very much interested in Research and Drug Discovery. Written 5 books and selected and working  as an  Editor, Associate Editor, Chief Advisory Board Member, Peer Reviewer , Reviewer for  52 reputed National and International Journals with good impact factors . Worked for more than 75  Research Projects and Guided  many Research works and currently guiding Pharm.D, B.Pharm students and working with M.Pharm Research works and working in collaboration with ESI hospital Bangalore for Monitoring Research, Clerkship and internship activities of Pharm.D students. Currently heading as Chief Biological Scientist in Animal Ethics Committee Chief Member of Human Ethics Committee ,Chief Member  of Research and Development Cell, Chief in charge for Seminars Conferences Workshops and In charge for Placements , Inspections and Examinations cells, Nodal Officer for National Scholarship Portal in Gautham College of Pharmacy Bangalore Karnataka India.

    and has participated in 100 National, International Conferences, U.G.C sponsored workshops, Webinars, Essay Competitions, Science Fares and Quiz Competitions, Talent search examinations and Achieved 64 Prizes and have Published 140 Research and Review papers in various National and International Journals with good impact factors and very much interested in Research and Drug Discovery and possess various memberships in research organizations.Written 5 books that are published by reputed Book Publishers. Selected and working as an editorial team of 35 reputed National and International Journals with good impact factors. Worked for more than 62 Research projects and Guided  many Research works and currently guiding Pharm.D, B.Pharmacy students and working with M.Pharmacy Research works and also working in collaboration with ESI Hospital Bangalore for Research works currently heading as Chief Biological scientist in Animal Ethics Committee and Member of Human Ethics Committee  along with Chief Member in Research and Development Cell along Chief in charge for Seminars Conferences Workshops and In charge for Placements , Inspections and examinations cells and Nodal Officer for National Scholarship Portal in Gautham College of Pharmacy Bangalore Karnataka India.

     

    AREAS OF RESEARCH INTERESTS : Clinical Research, Clinical Pharmacy, Drug Discovery and Development, Community Medicine, Pharmacological and Toxicological Studies, Pharmaco-Genomics, Pharmaco Epidemiology, Pharmaco-Economics, Epi-Genetic studies. Clinical Pharmaco-Kinetics, Pharmametrics,Operational Research, Pharmaco-Dynamics& Therapeutic Drug Monitoring.

     

     

     CONTACT DETAILS:

    Email: [email protected]

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    Mobile number: +917093543366

                                             

     

References

Harries AD, Lin Y, Kumar AMV, Satyanarayana S, Takarinda KC, Dlodlo RA, Zachariah R, Olliaro P. What can national T.B control programs in low-and middle-income countries do to end tuberculosis by 2030? F1000 Research. 2018; 7: 1011.

Fisher AA, Laing JE, Stoeckel JE, Townsend JW. Hand Book for Family Planning Operations Research Design, 2nd Ed. New York: Population Council; 1991.

World Health Organization. Framework for operations and implementation research in health. Geneva: WHO; 2018. Available from: http//www.who.int/hiv/pub/operational/frame work/en/Index. Hmtl (accessed on 2015 Apr 4).

Murthy PR. Operational Research. New Delhi: New Age International Publishers; 2007. 1–21p.

Churchman CW, Ackoff RL, Arnoff EL. Introduction to Operations Research. New York: John Wiley & Sons Inc.; 1957.

Zachariah R, Harries AD, Ishikawa N, Rieder HL, Bissell K, Laserson K, Massaquoi M, Herp MV, Reid T. Operational Research in low-income countries What, why and how? Lancet Infect Dis. 2009; 9(7): 11–17p.

Sharma D, Sarkar D. Pathophysiology of Tuberculosis: An Updated Review. Pharmatutor. 2018; 6(2): 15–21p.

Monks T. Operational research as implementation science: Definitions, challenges and research priorities. Implementation Science. 2016; 11: 81. DOCI: 1186/s 13012-016-044-0.

Wang Chen, Horby Peter W, Hayden Frederick G, Gao George F. A novel coronavirus outbreak of global health concern. The Lancet. 2020;395(10223):470–473 https://www.who.int/emergencies/ diseases/novel-coronavirus-2019?gclid=CjwKCAjw0On8BRAgEiwAincsHGeZZlRMAJYcoscb9 uiM3WBnCDZGSVnqwYYnMVAtOqZtY0SbK8HguBoC6fcQAvD_B

Who.int. (2023). 2019 Novel Coronavirus. Online Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019?gclid=

Padayatchi N, Daftary A, Naidu N, Naidoo K, Pai M. Tuberculosis: Treatment failure, or failure to treat? Lessons from India and South Africa. BMJ Glob Health. 2019; 4(1): e001097.

Pai M, Nicol MP, Boehme CC. Tuberculosis diagnostics: State of the art and future directions. Microbiol Spectr. 2016; 4(5): 7p.

Dash M. Drug resistant tuberculosis: A diagnostic challenge. J Postgrad Med. 2013; 59(3): 196e202.

Thakur H. Drug resistance in TB control—a global & Indian situation. J Prevent Med. 2008; 16(3e4): 3e9.

Sharma N, Khanna A, Chandra S, Basu S, Chopra KK, Singla N, Babbar N, Kohli C. Trends & treatment outcomes of multidrug-resistant tuberculosis in Delhi, India (2009-2014): a retrospective record-based study. Indian J Med Res. 2020; 151(6): 598e603.

Rawal T, Butani S. Combating tuberculosis infection: a forbidding challenge. Indian J Pharmaceut Sci. 2016; 78(1): 8e16.

Pai M, Furin J. Tuberculosis innovations mean little if they cannot save lives. eLife. 2017; 6: e25956.

Khaparde S. The national strategic plan for tuberculosis step toward ending tuberculosis by 2025. J Mahatma Gandhi Inst Med Sci. 2019; 24: 17e18.

Zachariah R, Spielmann MP, Chinji C, Gomani P, Arendt V, Hargreaves NJ, Salaniponi FM, Harries AD. Voluntary counselling, HIV testing and adjunctive cotrimoxazole reduces mortality in tuberculosis patients in Thyolo, Malawi. AIDS. 2003; 17: 1053–1061p.

Sai Babu B, Satyanarayana AV, Venkateshwaralu G, Ramakrishna U, Vikram P, Sahu S, Wares F, Dewan PK, Santosha K, Jyoti J, Srinath S, Chethana R, Neelima T, Vinod P, Yogesh M. Initial default among diagnosed sputum positive pulmonary tuberculosis patients in Andhra Pradesh, India. Int J Tuberc Lung Dis. 2008; 12: 1055–1058p.

Dr. Gunjan Kumar Public Health Panorama of Operational Research: A Narrative Review International journal of preventive medicine. 2019; 10: 43.

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Published

2023-05-08

Issue

Vol. 13 No. 1 (2023)

Section

Review Article

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